14-3-3 protein 3D structures

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**[[1yz5]], [[6tlg]] – hPRS – human<br />
**[[1yz5]], [[6tlg]] – hPRS – human<br />
-
*14-3-3 protein σ binary complex with peptide
+
*14-3-3 protein σ complex with peptide
 +
 
 +
**[[1ywt]], [[3iqj]], [[3iqu]], [[3lw1]], [[3mhr]], [[3p1n]], [[4dat]], [[4dau]], [[4fl5]], [[4jc3]], [[4jdd]], [[4iea]], [[4qli]], [[4y5i]], [[4y32]], [[4y3b]], [[5btv]], [[5hf3]], [[5mhc]], [[5moc]], [[5mxo]], [[5my9]], [[5myc]], [[5n5r]], [[5n5t]], [[5n5w]], [[5n75]], [[5ok9]], [[5okf]], [[5om0]], [[5oma]], [[6fau]], [[6fav]], [[6faw]], [[6fbb]], [[6fcp]], [[6fbw]], [[6fby]], [[6fi4]], [[6fi5]], [[6g6x]], [[6g8i]], [[6g8j]], [[6g8k]], [[6g8l]], [[6g8p]], [[6g8q]], [[6hhp]], [[6hkb]], [[6hkf]], [[6hmt]], [[6hmu]], [[6hn2]], [[6nv2]], [[6qiu]], [[6qdr]], [[6qds]], [[6qdt]], [[6qhl]], [[6qhm]], [[6qzr]], [[6qzs]], [[6r5l]], [[6rjz]], [[6rkk]], [[6rkm]], [[6rl3]], [[6s3c]], [[6s40]], [[6tjm]], [[6tl3]], [[6w0l]], [[6xwd]], [[6y1d]], [[6y1j]], [[6y3m]], [[6y3o]], [[6y3r]], [[6y3s]], [[6y3v]], [[6y40]], [[6y44]], [[6y58]], [[6y8a]], [[6y8b]], [[6y8d]], [[6y8e]], [[6ylu]], [[6yow]], [[6yox]], [[6yoy]], [[6yp2]], [[6yp3]], [[6yp8]], [[6ypl]], [[6ypy]], [[6yq2]], [[6zcj]], [[7aew]], [[7aog]], [[7b13]], [[7b15]], [[7bm9]], [[7nfw]], [[7nix]], [[7nma]], [[7nmw]], [[7nmx]], [[7nn2]], [[7nnd]], [[7nne]], [[7np2]], [[7npb]], [[7npg]], [[7o07]], [[7o6o]], [[7ob5]], [[7obc]], [[7obg]], [[7obk]], [[7obs]], [[7obx]], [[7qik]], [[7qip]] – hPRS + peptide <br />
 +
 
 +
**[[3p1p]], [[3p1r]], [[5lu1]], [[5lu2]] – hPRS (mutant) + peptide <br />
-
**[[3lw1]], [[5moc]], [[5mxo]], [[6r5l]], [[6rjz]], [[6rkk]], [[6rkm]], [[6rl3]], [[6s3c]], [[6s40]] – hPRS + p53 peptide <br />
 
-
**[[3iqj]], [[3iqu]], [[4iea]] – hPRS + Raf-1 peptide <br />
 
-
**[[3mhr]], [[6g6x]], [[6g8i]], [[6g8j]], [[6g8k]], [[6g8l]], [[6g8p]], [[6g8q]] – hPRS + YAP peptide <br />
 
-
**[[3p1n]] – hPRS + TASK-3 peptide <br />
 
-
**[[3p1p]], [[3p1r]] – hPRS (mutant) + TASK-3 peptide <br />
 
-
**[[4dat]], [[4dau]] – hPRS + PADI6 peptide <br />
 
-
**[[4jc3]], [[4jdd]], [[6hhp]], [[6hkb]], [[6hkf]], [[6hmt]], [[6hmu]], [[6hn2]], [[7nfw]] – hPRS + estrogen receptor peptide <br />
 
-
**[[4fl5]], [[5btv]], [[5hf3]], [[4y5i]], [[4y32]], [[4y3b]], [[6fau]], [[6fav]], [[6faw]], [[6fbw]], [[6fby]], [[6fi4]], [[6fi5]], [[6qhm]] – hPRS + tau protein peptide <br />
 
**[[5ltw]] – hPRS (mutant) + HSPB6 <br />
**[[5ltw]] – hPRS (mutant) + HSPB6 <br />
-
**[[5lu1]], [[5lu2]] – hPRS (mutant) + HSPB6 peptide<br />
+
**[[3iqv]], [[3o8i]], [[3p1o]], [[3ux0]], [[4fr3]], [[6ghp]], [[6xxc]], [[6xy5]], [[6y18]], [[6y3a]], [[7axn]], [[7ayf]], [[7az1]], [[7az2]], [[7b9m]], [[7b9r]], [[7b9t]], [[7ba3]], [[7ba5]], [[7ba6]], [[7ba7]], [[7ba8]], [[7ba9]], [[7baa]], [[7bab]], [[7bdp]], [[7bdt]], [[7bdy]], [[7bfw]], [[7bg3]], [[7bgq]], [[7bgr]], [[7bgv]], [[7bgw]], [[7bi3]], [[7biq]], [[7biw]], [[7biy]], ]]7bjb]], [[7bjf]], [[7bjl]], [[7bjw]], [[7bkh]], [[7bmc]], [[7nif]], [[7nig]], [[7niz]], [[7nj6]], [[7nj8]], [[7nj9]], [[7nja]], [[7njb]], [[7nk3]], [[7nk5]], [[7nle]], [[7nm3]], [[7nqp]], [[7nrk]], [[7nrl]], [[7nla]], [[7nm1]], [[7nm9]], [[7nmh]], [[7nr7]], [[7nsv]], [[7nv4]], [[7nvi]], [[7nws]], [[7nxs]], [[7nxt]], [[7nxw]], [[7nxy]], [[7ny4]], [[7nyf]], [[7nz6]], [[7nzg]], [[7nye]], [[7nyg]], [[7nzk]], [[7nzv]], [[7o34]], [[7o3a]], [[7o3f]], [[7o3p]], [[7o3q]], [[7o3r]], [[7o3s]], [[7o57]], [[7o59]], [[7o5a]], [[7o5c]], [[7o5d]], [[7o5f]], [[7o5g]], [[7o5o]], [[7o5p]], [[7o5s]], [[7o5u]], [[7o5x]], [[7o6f]], [[7o6g]], [[7o6i]], [[7o6j]], [[7o6k]], [[7o6m]], [[7ob8]], [[7obd]], [[7obh]], [[7obl]], [[7obt]], [[7oby]], [[7opw]], [[7oq7]], [[7oq8]], [[7oq9]], [[7oqa]], [[7oqg]], [[7oqj]], [[7oqs]], [[7oqu]], [[7oqw]], [[7or3]], [[7or5]], [[7or7]], [[7or8]], [[7org]], [[7orh]], [[7ors]], [[7ort]] – hPRS + peptide + stabilizer<br />
-
**[[4qli]] – hPRS + SNAI1 peptide <br />
+
**[[3p1q]], [[3p1s]], [[3spr]], [[3smk]], [[3sml]], [[3smm]], [[3smn]], [[3smo]], [[3sp5]] – hPRS (mutant) + peptide + stabilizer<br />
-
**[[6xwd]], [[7aew]] – hPRS + APN peptide <br />
+
 
-
**[[6y3m]] – hPRS + ATPase peptide <br />
+
 
-
**[[6y8e]] – hPRS + MLF1 peptide <br />
+
 
-
**[[6y3o]] – hPRS + CaMKK 2 peptide <br />
+
 
-
**[[6y8a]] – hPRS + CaMKK 2 phosphopeptide <br />
+
 
-
**[[6yow]], [[6yox]], [[6yoy]], [[6yp2]], [[6yp3]], [[6yp8]], [[6ypl]], [[6ypy]], [[6yq2]] – hPRS + peptide <br />
+
 
-
**[[1ywt]], [[5mhc]], [[6w0l]], [[6y3v]], [[6y40]], [[6y44]], [[6ylu]], [[6zcj]] – hPRS + phosphopeptide <br />
+
 
-
**[[5my9]], [[5myc]] – hPRS + LRRK2 peptide <br />
+
 
-
**[[5n5r]], [[5n5t]], [[5n5w]], [[5n75]] – hPRS + taz ps89 peptide <br />
+
 
-
**[[5ok9]], [[5okf]] – hPRS/HSPB6 <br />
+
 
-
**[[5om0]] – hPRS/GLI1 <br />
+
-
**[[5oma]] – hPRS/STRAD1 + peptide <br />
+
-
**[[6fbb]], [[6fcp]] – hPRS + Shroom3 <br />
+
-
**[[6fau]], [[6fav]], [[6faw]], [[6fbw]], [[6fby]], [[6fi4]], [[6fi5]] – hPRS + tau peptide <br />
+
-
**[[6nv2]], [[6qhl]] – hPRS + p65 peptide <br />
+
-
**[[6qdr]], [[6qds]] – hPRS + pak-6 peptide <br />
+
-
**[[6qdt]] – hPRS + RA-GEF-1 peptide <br />
+
-
**[[6qiu]] – hPRS + ataxin phosphopeptide <br />
+
-
**[[6y3r]], [[6y3s]] – hPRS + Gab2 phosphopeptide <br />
+
-
**[[6y8b]], [[6y8d]] – hPRS + caspase-2 phosphopeptide <br />
+
-
**[[6qzr]], [[6qzs]] – hPRS + FOXO1 peptide <br />
+
-
**[[6tjm]], [[6tl3]], [[6y1d]], [[6y58]] – hPRS + estrogen receptor phosphopeptide <br />
+
-
**[[6xxc]], [[6xy5]], [[6y18]], [[6y3w]] – hPRS + estrogen receptor phosphopeptide + stabilizer<br />
+
-
**[[6y1j]] – hPRS + NF-kappa-B peptide <br />
+
*14-3-3 protein σ binary complex with small molecule
*14-3-3 protein σ binary complex with small molecule
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**[[3u9x]], [[6tm7]] – hPRS + pyridoxal phosphate<br />
**[[3u9x]], [[6tm7]] – hPRS + pyridoxal phosphate<br />
**[[3t0l]], [[3t0m]], [[4dhm]], [[4dhn]], [[4dho]], [[4dhp]], [[4dhq]], [[4dhr]], [[4dhs]], [[4dht]], [[4dhu]] – hPRS + inhibitor<br />
**[[3t0l]], [[3t0m]], [[4dhm]], [[4dhn]], [[4dho]], [[4dhp]], [[4dhq]], [[4dhr]], [[4dhs]], [[4dht]], [[4dhu]] – hPRS + inhibitor<br />
-
**[[5oeh]], [[5oeg]] – hPRS + molecular tweezers<br />
+
**[[4hqw]], [[4hru]] – hPRS + molecular tweezers<br />
**[[6tlf]] – hPRS + IMP <br />
**[[6tlf]] – hPRS + IMP <br />
**[[6qdu]] – hPRS + phosphothreonine <br />
**[[6qdu]] – hPRS + phosphothreonine <br />
- 
-
*14-3-3 protein σ ternary complex with stabilizer
 
- 
-
**[[3p1o]], [[3ux0]], [[4fr3]], [[6ghp]] – hPRS + TASK-3 peptide + stabilizer<br />
 
-
**[[3p1q]], [[3p1s]], [[3spr]], [[3smk]], [[3sml]], [[3smm]], [[3smn]], [[3smo]], [[3sp5]] – hPRS (mutant) + TASK-3 peptide + stabilizer<br />
 
-
**[[3iqv]], [[3o8i]] – hPRS + Raf-1 peptide + stabilizer<br />
 
*14-3-3 protein ζ
*14-3-3 protein ζ
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**[[6uan]] – hPRS + Raf peptide – Cryo EM<br />
**[[6uan]] – hPRS + Raf peptide – Cryo EM<br />
**[[6zfd]] – hPRS/protein E6 <br />
**[[6zfd]] – hPRS/protein E6 <br />
-
**[[6zfg]] – hPRS/protein E6 + fusicoccin<br />
+
**[[6zfg]] – hPRS/protein E6 + stabilizer<br />
 +
**[[7q16]] – hPRS/BAD peptide <br />
 +
**[[4wrq]], [[6f08]], [[6f09]] – hPRS + peptide <br />
**[[1a4o]] – bPRS - bovine<br />
**[[1a4o]] – bPRS - bovine<br />
-
**[[1a37]] – bPRS + Raf peptide <br />
+
**[[1a37]], [[1a38]] – bPRS + peptide <br />
-
**[[1a38]] – bPRS + R18 peptide <br />
+
**[[7exe]] – mPRS + ADAM22 peptide - mouse<br />
-
**[[4wrq]] – hPRS + Chibby peptide <br />
+
-
**[[6f09]] – hPRS + ubiquitin peptide <br />
+
-
**[[6f08]] – hPRS + son of sevenless homolog peptide <br />
+
**[[6nyb]], [[6q0j]], [[6q0t]] – PRS + B-Raf + MKK1 – beet armyworm – Cryo EM<br />
**[[6nyb]], [[6q0j]], [[6q0t]] – PRS + B-Raf + MKK1 – beet armyworm – Cryo EM<br />
Line 76: Line 51:
**[[3rdh]] – hPRS <br />
**[[3rdh]] – hPRS <br />
**[[3rdh]] – hPRS/LKB1 <br />
**[[3rdh]] – hPRS/LKB1 <br />
-
**[[1qja]], [[1qjb]], [[6eww]] – hPRS + phosphopeptide <br />
+
**[[1qja]], [[1qjb]], [[2c1j]], [[2c1n]], [[2o02]], [[2v7d]], [[2wh0]], [[3cu8]], [[3nkx]], [[4bg6]], [[4fj3]], [[4hkc]], [[4ihl]], [[4n7g]], [[4n7y]], [[4n84]], [[5d2d]], [[5ewz]], [[5exa]], [[5j31]], [[5jm4]], [[5m35]], [[5m36]], [[5m37]], [[5nas]], [[5ulo]], [[6rlz]], [[6ejl]], [[6eww]], [[6f08]], [[7d8p]], [[7d9v]], [[7dh8]] – hPRS + peptide <br />
-
**[[2c1j]], [[2c1n]] – hPRS + histone H3 peptide <br />
+
 
-
**[[2o02]], [[4n7g]], [[4n7y]], [[4n84]], [[5j31]] – hPRS + exoenzyme S peptide <br />
+
-
**[[2v7d]], [[4hkc]] – hPRS + integrin peptide <br />
+
-
**[[5jm4]], [[6rlz]] – hPRS + peptide <br />
+
-
**[[5nas]] – hPRS + PI4KIIIB peptide <br />
+
-
**[[5m35]], [[5m36]], [[5m37]] – hPRS + M-phase phosphatase peptide <br />
+
-
**[[5ulo]] – hPRS + TBC1D7 peptide <br />
+
-
**[[6ejl]] – hPRS + MAP3K 5 peptide <br />
+
-
**[[6f08]] – hPRS + SOS-1 peptide <br />
+
-
**[[3cu8]], [[3nkx]], [[4fj3]], [[4ihl]] – hPRS + Raf-1 peptide <br />
+
-
**[[6u2h]], [[6xag]] – hPRS + B-Raf <br />
+
-
**[[6q0k]] – hPRS + B-Raf – Cryo EM<br />
+
-
**[[2wh0]] – hPRS + protein kinase C ε peptide <br />
+
-
**[[4bg6]] – hPRS + RND3 peptide <br />
+
-
**[[5ewz]], [[5exa]] – hPRS + GRB2-associated protein peptide <br />
+
-
**[[5d2d]] – hPRS + CFTR peptide <br />
+
**[[5d3f]] – hPRS + CFTR peptide + stabilizer<br />
**[[5d3f]] – hPRS + CFTR peptide + stabilizer<br />
 +
 +
 +
**[[6u2h]], [[6xag]] – hPRS + B-Raf <br />
 +
**[[6q0k]], [[7mfe]] – hPRS + B-Raf – Cryo EM<br />
 +
**[[7mff]] – hPRS + B-Raf + inhibitor – Cryo EM<br />
 +
**[[7mfd]] – hPRS + B-Raf + MEK – Cryo EM<br />
 +
**[[1ib1]] – hPRS + serotonin N-acetyltransferase <br />
**[[1ib1]] – hPRS + serotonin N-acetyltransferase <br />
**[[6fn9]], [[6fna]], [[6fnb]], [[6fnc]] – hPRS + inhibitor<br />
**[[6fn9]], [[6fna]], [[6fnb]], [[6fnc]] – hPRS + inhibitor<br />
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**[[4e2e]] – hPRS <br />
**[[4e2e]] – hPRS <br />
-
**[[2b05]] – hPRS + phosphopeptide <br />
+
**[[2b05]], [[3uzd]], [[4j6s]], [[4o46]], [[5d3e]], [[6a5q]], [[6byj]], [[6byl]], [[6fel]], [[6gkf]], [[6gkg]], [[6s9k]], [[6sad]], [[7a6r]], [[7a6y]] – hPRS + peptide <br />
-
**[[3uzd]] – hPRS + histone deacylase peptide <br />
+
-
**[[4j6s]] – hPRS + tyrosine hydroxylase peptide <br />
+
-
**[[4o46]] – hPRS + influenza C-terminal peptide <br />
+
-
**[[5d3e]] – hPRS + CFTR peptide <br />
+
-
**[[6fel]] – hPRS + CaMKK 2 peptide <br />
+
-
**[[6y4k]], [[6y6b]] – hPRS + CaMKK 2 peptide + fusicoccin A<br />
+
-
**[[6a5q]] – hPRS + TFEB peptide <br />
+
-
**[[6gkf]], [[6gkg]], [[6s9k]], [[6sad]] – hPRS + caspase-2 peptide <br />
+
-
**[[6byj]], [[6byl]] – hPRS + O-GlcNAc peptide <br />
+
**[[6bzd]] – hPRS (mutant) + O-GlcNAc peptide <br />
**[[6bzd]] – hPRS (mutant) + O-GlcNAc peptide <br />
 +
**[[6y4k]], [[6y6b]] – hPRS + CaMKK 2 peptide + stabilizer<br />
 +
 +
*14-3-3 protein β
 +
 +
**[[7qi1]] – hPRS + CFTR peptide + stabilizer<br />
*14-3-3 protein β/α
*14-3-3 protein β/α
**[[2bq0]], [[4dnk]] – hPRS <br />
**[[2bq0]], [[4dnk]] – hPRS <br />
-
**[[2c23]], [[6gn0]], [[6gn8]], [[6gnj]], [[6gnk]] – hPRS + exoenzyme S peptide <br />
+
**[[2c23]], [[5n10]], [[6a5q]], [[6byk]], [[6gn0]], [[6gn8]], [[6gnj]], [[6gnk]], [[6gnn]], [[6hep]] – hPRS + peptide <br />
-
**[[6gnn]] – hPRS + exoenzyme T peptide <br />
+
-
**[[5n10]] – hPRS + estrogen receptor peptide <br />
+
-
**[[6a5q]] – hPRS + TFEB peptide <br />
+
-
**[[6byk]] – hPRS + O-GlcNAc peptide <br />
+
-
**[[6hep]] – hPRS + CFTR peptide <br />
+
**[[6ygj]] – hPRS + ChREBP peptide + stabilizer<br />
**[[6ygj]] – hPRS + ChREBP peptide + stabilizer<br />
-
**[[4gnt]] – mPRS + ChREBP peptide - mouse<br />
+
**[[4gnt]] – mPRS + ChREBP peptide <br />
**[[5f74]] – mPRS + ChREBP + AMP<br />
**[[5f74]] – mPRS + ChREBP + AMP<br />
**[[5wfu]] – mPRS + malate <br />
**[[5wfu]] – mPRS + malate <br />
- 
*14-3-3 protein θ
*14-3-3 protein θ
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**[[2c63]], [[2c74]] – hPRS + phosphopeptide <br />
**[[2c63]], [[2c74]] – hPRS + phosphopeptide <br />
**[[5yqg]] – hPRS + NUMB peptide <br />
**[[5yqg]] – hPRS + NUMB peptide <br />
 +
**[[7nmz]] – hPRS + E3 ubiquitin-protein ligase NEDD4-like <br />
*14-3-3 protein ε
*14-3-3 protein ε
Line 142: Line 100:
**[[2br9]], [[6eih]] – hPRS + phosphopeptide <br />
**[[2br9]], [[6eih]] – hPRS + phosphopeptide <br />
**[[3ual]], [[3ubw]] – hPRS + myeloid leukemia factor 1 peptide <br />
**[[3ual]], [[3ubw]] – hPRS + myeloid leukemia factor 1 peptide <br />
 +
**[[7c8e]] – hPRS + 9J10 peptide <br />
*14-3-3 protein
*14-3-3 protein
-
**[[3efz]] – PRS + phosphoserine – ''Cryptosporidium parvum''<br />
+
**[[3efz]] – PRS + phosphoserine – Cryptosporidium parvum<br />
-
**[[4f7r]] – PRS – ''Giardia intestinalis''<br />
+
**[[4f7r]] – PRS – Giardia intestinalis<br />
*14-3-3-like protein C
*14-3-3-like protein C
Line 162: Line 121:
**[[4dx0]] – tPRS + PMA2 peptide + stabilizer<br />
**[[4dx0]] – tPRS + PMA2 peptide + stabilizer<br />
 +
}}
}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Revision as of 08:50, 11 August 2022

3D structures of 14-3-3 protein

Updated on 11-August-2022 - For a general description of the protein see 14-3-3 protein







Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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