7bpu
From Proteopedia
(Difference between revisions)
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==Structural and mechanistic insights into the biosynthesis of Digeranylgeranylglyceryl phosphate synthase in membranes== | ==Structural and mechanistic insights into the biosynthesis of Digeranylgeranylglyceryl phosphate synthase in membranes== | ||
| - | <StructureSection load='7bpu' size='340' side='right'caption='[[7bpu]]' scene=''> | + | <StructureSection load='7bpu' size='340' side='right'caption='[[7bpu]], [[Resolution|resolution]] 3.32Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BPU FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7bpu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BPU FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bpu OCA], [https://pdbe.org/7bpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bpu RCSB], [https://www.ebi.ac.uk/pdbsum/7bpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bpu ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MJ0279 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Geranylgeranylglycerol-phosphate_geranylgeranyltransferase Geranylgeranylglycerol-phosphate geranylgeranyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.42 2.5.1.42] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bpu OCA], [https://pdbe.org/7bpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bpu RCSB], [https://www.ebi.ac.uk/pdbsum/7bpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bpu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DGGGP_METJA DGGGP_METJA]] Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Geranylgeranylglycerol-phosphate geranylgeranyltransferase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Cheng W]] | + | [[Category: Metja]] |
| - | [[Category: Ren | + | [[Category: Cheng, W]] |
| + | [[Category: Ren, S]] | ||
| + | [[Category: Lipid]] | ||
| + | [[Category: Membrane protein]] | ||
Revision as of 06:29, 18 August 2022
Structural and mechanistic insights into the biosynthesis of Digeranylgeranylglyceryl phosphate synthase in membranes
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