7rj4
From Proteopedia
(Difference between revisions)
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==Co-crystal structure of lenacapavir bound to N74D mutant of disulfide stabilized HIV-1 CA hexamer== | ==Co-crystal structure of lenacapavir bound to N74D mutant of disulfide stabilized HIV-1 CA hexamer== | ||
| - | <StructureSection load='7rj4' size='340' side='right'caption='[[7rj4]]' scene=''> | + | <StructureSection load='7rj4' size='340' side='right'caption='[[7rj4]], [[Resolution|resolution]] 3.32Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RJ4 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7rj4]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RJ4 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rj4 OCA], [https://pdbe.org/7rj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rj4 RCSB], [https://www.ebi.ac.uk/pdbsum/7rj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rj4 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=QNG:N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide'>QNG</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7rar|7rar]], [[7rao|7rao]], [[7rhn|7rhn]], [[7rhm|7rhm]], [[7rj2|7rj2]]</div></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rj4 OCA], [https://pdbe.org/7rj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rj4 RCSB], [https://www.ebi.ac.uk/pdbsum/7rj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rj4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bester | + | [[Category: Bester, S M]] |
| - | [[Category: Kvaratskhelia M]] | + | [[Category: Kvaratskhelia, M]] |
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Viral protein]] | ||
| + | [[Category: Viral protein-inhibitor complex]] | ||
Revision as of 06:39, 18 August 2022
Co-crystal structure of lenacapavir bound to N74D mutant of disulfide stabilized HIV-1 CA hexamer
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