7yxa

<StructureSection load='7yxa' size='340' side='right'caption='[[7yxa]], [[Resolution|resolution]] 2.20&Aring;' scene=''>

<table><tr><td colspan='2'>[[7yxa]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YXA FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B2O:4-[6-(2-naphthalen-1-ylethoxy)-2,3,4,5-tetrahydro-1H-3-benzazepin-3-ium-3-yl]butanoic+acid'>B2O</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yxa OCA], [https://pdbe.org/7yxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yxa RCSB], [https://www.ebi.ac.uk/pdbsum/7yxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yxa ProSAT]</span></td></tr>

== Function ==

[[https://www.uniprot.org/uniprot/S1PR5_HUMAN S1PR5_HUMAN]] Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.

[[Category: Borshchevskiy, V]]

[[Category: Bourenkov, G]]

[[Category: Bukhdruker, S]]

[[Category: Cherezov, V]]

[[Category: Cho, Y]]

[[Category: Ergasheva, M]]

[[Category: Gerasimov, A]]

[[Category: Gordeliy, V]]

[[Category: Gusach, A]]

[[Category: Gushchin, I]]

[[Category: Hu, H]]

[[Category: Huyn, H J]]

[[Category: Khorn, P]]

[[Category: Khusainov, G]]

[[Category: Kovalev, K]]

[[Category: Kovaleva, M]]

[[Category: Liu, W]]

[[Category: Luginina, A]]

[[Category: Lyapina, E]]

[[Category: Marin, E]]

[[Category: Mishin, A]]

[[Category: Okhrimenko, I]]

[[Category: Orekhov, P]]

[[Category: Park, G]]

[[Category: Park, J]]

[[Category: Park, S]]

[[Category: Popov, P]]

[[Category: Rogachev, A]]

[[Category: Shevtsov, M]]

[[Category: Vakhrameev, D]]

[[Category: Weierstall, U]]

[[Category: Xfel]]