This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3zwx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal structure of ADP-ribosyl cyclase complexed with 8-bromo-ADP- ribose==
==Crystal structure of ADP-ribosyl cyclase complexed with 8-bromo-ADP- ribose==
-
<StructureSection load='3zwx' size='340' side='right' caption='[[3zwx]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
+
<StructureSection load='3zwx' size='340' side='right'caption='[[3zwx]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3zwx]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZWX FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3zwx]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZWX FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AV1:[(2R,3S,4R,5R)-5-(6-AMINO-8-BROMO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+[(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>AV1</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AV1:[(2R,3S,4R,5R)-5-(6-AMINO-8-BROMO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+[(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>AV1</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1r0s|1r0s]], [[3zwn|3zwn]], [[1lbe|1lbe]], [[1r16|1r16]], [[3zwo|3zwo]], [[3zwp|3zwp]], [[1r12|1r12]], [[1r15|1r15]], [[3zwv|3zwv]], [[3zwy|3zwy]], [[3zww|3zww]]</td></tr>
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1r0s|1r0s]], [[3zwn|3zwn]], [[1lbe|1lbe]], [[1r16|1r16]], [[3zwo|3zwo]], [[3zwp|3zwp]], [[1r12|1r12]], [[1r15|1r15]], [[3zwv|3zwv]], [[3zwy|3zwy]], [[3zww|3zww]]</div></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr>
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zwx OCA], [http://pdbe.org/3zwx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zwx RCSB], [http://www.ebi.ac.uk/pdbsum/3zwx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zwx ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zwx OCA], [https://pdbe.org/3zwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zwx RCSB], [https://www.ebi.ac.uk/pdbsum/3zwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zwx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NADA_APLCA NADA_APLCA]] Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for calcium mobilization from endoplasmic reticulum. Also has cADPr hydrolase activity.<ref>PMID:11829748</ref>
+
[[https://www.uniprot.org/uniprot/NADA_APLCA NADA_APLCA]] Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for calcium mobilization from endoplasmic reticulum. Also has cADPr hydrolase activity.<ref>PMID:11829748</ref>
==See Also==
==See Also==
Line 19: Line 19:
</StructureSection>
</StructureSection>
[[Category: Aplca]]
[[Category: Aplca]]
 +
[[Category: Large Structures]]
[[Category: Graeff, R]]
[[Category: Graeff, R]]
[[Category: Hao, Q]]
[[Category: Hao, Q]]

Revision as of 07:24, 18 August 2022

Crystal structure of ADP-ribosyl cyclase complexed with 8-bromo-ADP- ribose

PDB ID 3zwx

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3zwx"
Personal tools