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4ae7

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<StructureSection load='4ae7' size='340' side='right'caption='[[4ae7]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='4ae7' size='340' side='right'caption='[[4ae7]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ae7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AE7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AE7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ae7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AE7 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ae8|4ae8]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4ae8|4ae8]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ae7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ae7 OCA], [http://pdbe.org/4ae7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ae7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ae7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ae7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ae7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ae7 OCA], [https://pdbe.org/4ae7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ae7 RCSB], [https://www.ebi.ac.uk/pdbsum/4ae7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ae7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ACO15_HUMAN ACO15_HUMAN]] Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleyl-CoA and other unsaturated long-chain fatty acid-CoA esters. Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function.<ref>PMID:22586271</ref>
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[[https://www.uniprot.org/uniprot/ACO15_HUMAN ACO15_HUMAN]] Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleyl-CoA and other unsaturated long-chain fatty acid-CoA esters. Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function.<ref>PMID:22586271</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Bleck, C K.E]]
[[Category: Bleck, C K.E]]
[[Category: Cron, P]]
[[Category: Cron, P]]

Revision as of 05:31, 25 August 2022

Crystal structure of human THEM5

PDB ID 4ae7

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