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4afz

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<StructureSection load='4afz' size='340' side='right'caption='[[4afz]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='4afz' size='340' side='right'caption='[[4afz]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4afz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AFZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4afz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human] and [https://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AFZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1klt|1klt]], [[1pjp|1pjp]], [[1nn6|1nn6]], [[4afu|4afu]], [[1t31|1t31]], [[4afq|4afq]], [[4afs|4afs]], [[4ag1|4ag1]], [[4ag2|4ag2]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1klt|1klt]], [[1pjp|1pjp]], [[1nn6|1nn6]], [[4afu|4afu]], [[1t31|1t31]], [[4afq|4afq]], [[4afs|4afs]], [[4ag1|4ag1]], [[4ag2|4ag2]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymase Chymase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.39 3.4.21.39] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chymase Chymase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.39 3.4.21.39] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4afz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4afz OCA], [http://pdbe.org/4afz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4afz RCSB], [http://www.ebi.ac.uk/pdbsum/4afz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4afz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4afz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4afz OCA], [https://pdbe.org/4afz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4afz RCSB], [https://www.ebi.ac.uk/pdbsum/4afz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4afz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN]] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
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[[https://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN]] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Chymase]]
[[Category: Chymase]]
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Synthetic construct sequences]]
[[Category: Synthetic construct sequences]]
[[Category: Banner, D W]]
[[Category: Banner, D W]]

Revision as of 05:32, 25 August 2022

Human Chymase - Fynomer Complex

PDB ID 4afz

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