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4aq5
From Proteopedia
(Difference between revisions)
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<SX load='4aq5' size='340' side='right' viewer='molstar' caption='[[4aq5]], [[Resolution|resolution]] 6.20Å' scene=''> | <SX load='4aq5' size='340' side='right' viewer='molstar' caption='[[4aq5]], [[Resolution|resolution]] 6.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4aq5]] is a 5 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4aq5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AQ5 FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1l4w|1l4w]], [[1ljz|1ljz]], [[1oed|1oed]], [[2bg9|2bg9]], [[4aq9|4aq9]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1l4w|1l4w]], [[1ljz|1ljz]], [[1oed|1oed]], [[2bg9|2bg9]], [[4aq9|4aq9]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4aq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aq5 OCA], [https://pdbe.org/4aq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4aq5 RCSB], [https://www.ebi.ac.uk/pdbsum/4aq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4aq5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ACHA_TORMA ACHA_TORMA]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 05:42, 25 August 2022
Gating movement in acetylcholine receptor analysed by time-resolved electron cryo-microscopy (closed class)
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