4azr
From Proteopedia
(Difference between revisions)
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<StructureSection load='4azr' size='340' side='right'caption='[[4azr]], [[Resolution|resolution]] 2.95Å' scene=''> | <StructureSection load='4azr' size='340' side='right'caption='[[4azr]], [[Resolution|resolution]] 2.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4azr]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4azr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AZR FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A9M:N-(2-HYDROXYETHYL)ICOSANAMIDE'>A9M</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A9M:N-(2-HYDROXYETHYL)ICOSANAMIDE'>A9M</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1b56|1b56]], [[1jjj|1jjj]], [[4azm|4azm]], [[4azn|4azn]], [[4azo|4azo]], [[4azp|4azp]], [[4azq|4azq]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1b56|1b56]], [[1jjj|1jjj]], [[4azm|4azm]], [[4azn|4azn]], [[4azo|4azo]], [[4azp|4azp]], [[4azq|4azq]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4azr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4azr OCA], [https://pdbe.org/4azr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4azr RCSB], [https://www.ebi.ac.uk/pdbsum/4azr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4azr ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN]] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Fatty acid-binding protein|Fatty acid-binding protein]] | + | *[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Deutsch, D]] | [[Category: Deutsch, D]] | ||
[[Category: Kaczocha, M]] | [[Category: Kaczocha, M]] | ||
Revision as of 05:52, 25 August 2022
Human epidermal fatty acid-binding protein (FABP5) in complex with the endocannabinoid anandamide
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