4b6c
From Proteopedia
(Difference between revisions)
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==Structure of the M. smegmatis GyrB ATPase domain in complex with an aminopyrazinamide== | ==Structure of the M. smegmatis GyrB ATPase domain in complex with an aminopyrazinamide== | ||
| - | <StructureSection load='4b6c' size='340' side='right' caption='[[4b6c]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='4b6c' size='340' side='right'caption='[[4b6c]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4b6c]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4b6c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_smegmatis"_trevisan_1889 "bacillus smegmatis" trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B6C FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B5U:6-(3,4-DIMETHYLPHENYL)-3-[[4-[3-(4-METHYLPIPERAZIN-1-YL)PROPOXY]PHENYL]AMINO]PYRAZINE-2-CARBOXAMIDE'>B5U</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B5U:6-(3,4-DIMETHYLPHENYL)-3-[[4-[3-(4-METHYLPIPERAZIN-1-YL)PROPOXY]PHENYL]AMINO]PYRAZINE-2-CARBOXAMIDE'>B5U</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gyrB ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gyrB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1772 "Bacillus smegmatis" Trevisan 1889])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6c OCA], [https://pdbe.org/4b6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b6c RCSB], [https://www.ebi.ac.uk/pdbsum/4b6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6c ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/GYRB_MYCSM GYRB_MYCSM]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Gyrase|Gyrase]] | + | *[[Gyrase 3D Structures|Gyrase 3D Structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bacillus smegmatis trevisan 1889]] | [[Category: Bacillus smegmatis trevisan 1889]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Basu, R]] | [[Category: Basu, R]] | ||
[[Category: Ghorpade, S]] | [[Category: Ghorpade, S]] | ||
Revision as of 07:01, 31 August 2022
Structure of the M. smegmatis GyrB ATPase domain in complex with an aminopyrazinamide
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