4b8z

<table><tr><td colspan='2'>[[4b8z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B8Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B8Z FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4b8w|4b8w]]</td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/GDP-L-fucose_synthase GDP-L-fucose synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.271 1.1.1.271] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b8z OCA], [http://pdbe.org/4b8z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b8z RCSB], [http://www.ebi.ac.uk/pdbsum/4b8z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b8z ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/FCL_HUMAN FCL_HUMAN]] Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.