This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7zik
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor LP533401== | |
| - | + | <StructureSection load='7zik' size='340' side='right'caption='[[7zik]], [[Resolution|resolution]] 2.59Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7zik]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZIK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZIK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=IVN:(2~{R})-2-azanyl-3-[4-[2-azanyl-6-[(1~{R})-1-[4-chloranyl-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]phenyl]propanoic+acid'>IVN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zik OCA], [https://pdbe.org/7zik PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zik RCSB], [https://www.ebi.ac.uk/pdbsum/7zik PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zik ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/TPH1_HUMAN TPH1_HUMAN]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Heinemann U]] | ||
| + | [[Category: Schuetz A]] | ||
Revision as of 16:41, 7 September 2022
Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor LP533401
| |||||||||||
