8e6b
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of MERS 3CL protease in complex with a dimethyl sulfinyl benzene inhibitor== | |
| - | + | <StructureSection load='8e6b' size='340' side='right'caption='[[8e6b]], [[Resolution|resolution]] 1.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8e6b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E6B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UO9:(2~{S})-2-[[(2~{S})-4-methyl-2-[[2-methyl-2-[oxidanyl(phenyl)-$l^{3}-sulfanyl]propoxy]carbonylamino]pentanoyl]amino]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propane-1-sulfonic+acid'>UO9</scene>, <scene name='pdbligand=URR:N~2~-(ethoxycarbonyl)-N-{(1S,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-1-sulfanylpropan-2-yl}-L-leucinamide'>URR</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e6b OCA], [https://pdbe.org/8e6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e6b RCSB], [https://www.ebi.ac.uk/pdbsum/8e6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e6b ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[https://www.uniprot.org/uniprot/A0A1L2E0X0_MERS A0A1L2E0X0_MERS]] |
| - | [[Category: Groutas | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Middle East respiratory syndrome-related coronavirus]] | ||
| + | [[Category: Battaile KP]] | ||
| + | [[Category: Dampalla CS]] | ||
| + | [[Category: Groutas WC]] | ||
| + | [[Category: Liu L]] | ||
| + | [[Category: Lovell S]] | ||
Revision as of 16:42, 7 September 2022
Crystal structure of MERS 3CL protease in complex with a dimethyl sulfinyl benzene inhibitor
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