7q06
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Crystal structure of TPADO in complex with 2-OH-TPA== |
| - | <StructureSection load='7q06' size='340' side='right'caption='[[7q06]]' scene=''> | + | <StructureSection load='7q06' size='340' side='right'caption='[[7q06]], [[Resolution|resolution]] 1.95Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7q06]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Comamonas_sp. Comamonas sp.] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q06 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q06 OCA], [https://pdbe.org/7q06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q06 RCSB], [https://www.ebi.ac.uk/pdbsum/7q06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q06 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8IB:2-Hydroxyterephthalic+acid'>8IB</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q06 OCA], [https://pdbe.org/7q06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q06 RCSB], [https://www.ebi.ac.uk/pdbsum/7q06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q06 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/TPDB1_COMSP TPDB1_COMSP]] Component of the terephthalate 1,2-dioxygenase multicomponent enzyme system which catalyzes the dioxygenation of terephthalate (TER/TPA) to 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylic acid (DCD). It can also use 2,5-dicarboxypyridine (PDC) and 1,4-napthalenedicarboxylic acid (NDC) as substrates, and preferentially uses NADPH which is the physiological electron donor.<ref>PMID:16517628</ref> <ref>PMID:18776687</ref> <ref>PMID:7961417</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Comamonas sp]] | ||
| + | [[Category: Gallus gallus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: DuBois JL]] |
| + | [[Category: Kincannon WM]] | ||
| + | [[Category: McGeehan JE]] | ||
| + | [[Category: Zahn M]] | ||
Revision as of 16:48, 7 September 2022
Crystal structure of TPADO in complex with 2-OH-TPA
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