7rpm
From Proteopedia
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==Structures of the Intracellular Domain and Transmembrane Domain of the Human alpha7 Nicotinic Acetylcholine Receptors== | ==Structures of the Intracellular Domain and Transmembrane Domain of the Human alpha7 Nicotinic Acetylcholine Receptors== | ||
| - | <StructureSection load='7rpm' size='340' side='right'caption='[[7rpm | + | <StructureSection load='7rpm' size='340' side='right'caption='[[7rpm]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[7rpm]] is a 5 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RPM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RPM FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7rpm]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RPM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RPM FirstGlance]. <br> |
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rpm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rpm OCA], [https://pdbe.org/7rpm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rpm RCSB], [https://www.ebi.ac.uk/pdbsum/7rpm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rpm ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rpm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rpm OCA], [https://pdbe.org/7rpm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rpm RCSB], [https://www.ebi.ac.uk/pdbsum/7rpm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rpm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [[https://www.uniprot.org/uniprot/ACHA7_HUMAN ACHA7_HUMAN]] 15q13.3 microdeletion syndrome. | + | [[https://www.uniprot.org/uniprot/ACHA7_HUMAN ACHA7_HUMAN]] 15q13.3 microdeletion syndrome. |
== Function == | == Function == | ||
| - | [[https://www.uniprot.org/uniprot/ACHA7_HUMAN ACHA7_HUMAN]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin. | + | [[https://www.uniprot.org/uniprot/ACHA7_HUMAN ACHA7_HUMAN]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bondarenko | + | [[Category: Bondarenko V]] |
| - | [[Category: Chen | + | [[Category: Chen Q]] |
| - | [[Category: Tang | + | [[Category: Tang P]] |
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Revision as of 16:48, 7 September 2022
Structures of the Intracellular Domain and Transmembrane Domain of the Human alpha7 Nicotinic Acetylcholine Receptors
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