7uwj

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====
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==Structure of the homodimeric IL-25-IL-17RB binary complex==
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<StructureSection load='7uwj' size='340' side='right'caption='[[7uwj]]' scene=''>
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<StructureSection load='7uwj' size='340' side='right'caption='[[7uwj]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7uwj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UWJ FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uwj OCA], [https://pdbe.org/7uwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uwj RCSB], [https://www.ebi.ac.uk/pdbsum/7uwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uwj ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uwj OCA], [https://pdbe.org/7uwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uwj RCSB], [https://www.ebi.ac.uk/pdbsum/7uwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uwj ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/IL25_HUMAN IL25_HUMAN]] Induces activation of NF-kappa-B and stimulates production of the pro-inflammatory chemokine IL-8. Pro-inflammatory cytokine favoring Th2-type immune responses.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Caveney NA]]
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[[Category: Garcia KC]]
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[[Category: Jude KM]]
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[[Category: Wilson SC]]

Revision as of 16:49, 7 September 2022

Structure of the homodimeric IL-25-IL-17RB binary complex

PDB ID 7uwj

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