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7uwl
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Structure of the IL-25-IL-17RB-IL-17RA ternary complex== |
| - | <StructureSection load='7uwl' size='340' side='right'caption='[[7uwl]]' scene=''> | + | <StructureSection load='7uwl' size='340' side='right'caption='[[7uwl]], [[Resolution|resolution]] 3.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7uwl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UWL FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uwl OCA], [https://pdbe.org/7uwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uwl RCSB], [https://www.ebi.ac.uk/pdbsum/7uwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uwl ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uwl OCA], [https://pdbe.org/7uwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uwl RCSB], [https://www.ebi.ac.uk/pdbsum/7uwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uwl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/IL25_HUMAN IL25_HUMAN]] Induces activation of NF-kappa-B and stimulates production of the pro-inflammatory chemokine IL-8. Pro-inflammatory cytokine favoring Th2-type immune responses. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Caveney NA]] |
| + | [[Category: Garcia KC]] | ||
| + | [[Category: Jude KM]] | ||
| + | [[Category: Wilson SC]] | ||
Revision as of 16:49, 7 September 2022
Structure of the IL-25-IL-17RB-IL-17RA ternary complex
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