7xd0
From Proteopedia
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| - | ==== | + | ==cryo-EM structure of H2BK34ub nucleosome== |
| - | <StructureSection load='7xd0' size='340' side='right'caption='[[7xd0]]' scene=''> | + | <StructureSection load='7xd0' size='340' side='right'caption='[[7xd0]], [[Resolution|resolution]] 3.48Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7xd0]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XD0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XD0 FirstGlance]. <br> |
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xd0 OCA], [https://pdbe.org/7xd0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xd0 RCSB], [https://www.ebi.ac.uk/pdbsum/7xd0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xd0 ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xd0 OCA], [https://pdbe.org/7xd0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xd0 RCSB], [https://www.ebi.ac.uk/pdbsum/7xd0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xd0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/A0A672PXK1_SINGR A0A672PXK1_SINGR]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.[ARBA:ARBA00002001][RuleBase:RU000528] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Synthetic construct]] |
| + | [[Category: Ai HS]] | ||
| + | [[Category: Liu AJ]] | ||
| + | [[Category: Liu L]] | ||
| + | [[Category: Lou ZY]] | ||
Revision as of 16:50, 7 September 2022
cryo-EM structure of H2BK34ub nucleosome
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Categories: Homo sapiens | Large Structures | Synthetic construct | Ai HS | Liu AJ | Liu L | Lou ZY
