4c49

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<StructureSection load='4c49' size='340' side='right'caption='[[4c49]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4c49' size='340' side='right'caption='[[4c49]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4c49]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C49 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C49 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4c49]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C49 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C49 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HCY:(11ALPHA,14BETA)-11,17,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE'>HCY</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCY:(11ALPHA,14BETA)-11,17,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE'>HCY</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c41|4c41]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c49 OCA], [https://pdbe.org/4c49 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c49 RCSB], [https://www.ebi.ac.uk/pdbsum/4c49 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c49 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c49 OCA], [http://pdbe.org/4c49 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4c49 RCSB], [http://www.ebi.ac.uk/pdbsum/4c49 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4c49 ProSAT]</span></td></tr>
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</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/CBG_HUMAN CBG_HUMAN]] Corticosteroid-binding globulin deficiency. The disease is caused by mutations affecting the gene represented in this entry.
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[[https://www.uniprot.org/uniprot/CBG_HUMAN CBG_HUMAN]] Corticosteroid-binding globulin deficiency. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CBG_HUMAN CBG_HUMAN]] Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.<ref>PMID:18513745</ref>
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[[https://www.uniprot.org/uniprot/CBG_HUMAN CBG_HUMAN]] Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.<ref>PMID:18513745</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chan, W L]]
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[[Category: Chan WL]]
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[[Category: Read, R J]]
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[[Category: Read RJ]]
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[[Category: Zhou, A]]
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[[Category: Zhou A]]
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[[Category: Corticosteroid binding globulin]]
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[[Category: Hormone carrier]]
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[[Category: Serpin]]
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[[Category: Transport protein]]
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Revision as of 17:25, 7 September 2022

Reactive loop cleaved human CBG in complex with cortisol

PDB ID 4c49

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