7x39
From Proteopedia
(Difference between revisions)
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==Structure of CIZ1 bound ERH== | ==Structure of CIZ1 bound ERH== | ||
| - | <StructureSection load='7x39' size='340' side='right'caption='[[7x39]]' scene=''> | + | <StructureSection load='7x39' size='340' side='right'caption='[[7x39]], [[Resolution|resolution]] 2.85Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X39 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7x39]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X39 FirstGlance]. <br> |
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x39 OCA], [https://pdbe.org/7x39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x39 RCSB], [https://www.ebi.ac.uk/pdbsum/7x39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x39 ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x39 OCA], [https://pdbe.org/7x39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x39 RCSB], [https://www.ebi.ac.uk/pdbsum/7x39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x39 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [[https://www.uniprot.org/uniprot/CIZ1_HUMAN CIZ1_HUMAN]] Adult-onset cervical dystonia, DYT23 type. Defects in CIZ1 may be a cause of adult onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk. | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/CIZ1_HUMAN CIZ1_HUMAN]] May regulate the subcellular localization of CIP/WAF1.[[https://www.uniprot.org/uniprot/ERH_HUMAN ERH_HUMAN]] May have a role in the cell cycle. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Wang X]] | [[Category: Wang X]] | ||
[[Category: Xu C]] | [[Category: Xu C]] | ||
Revision as of 19:32, 7 September 2022
Structure of CIZ1 bound ERH
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