7zzk
From Proteopedia
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<StructureSection load='7zzk' size='340' side='right'caption='[[7zzk]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='7zzk' size='340' side='right'caption='[[7zzk]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[7zzk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZZK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZZK FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7zzk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ralstonia_solanacearum Ralstonia solanacearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZZK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZZK FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/N-acylhexosamine_oxidase N-acylhexosamine oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.29 1.1.3.29] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zzk OCA], [https://pdbe.org/7zzk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zzk RCSB], [https://www.ebi.ac.uk/pdbsum/7zzk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zzk ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zzk OCA], [https://pdbe.org/7zzk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zzk RCSB], [https://www.ebi.ac.uk/pdbsum/7zzk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zzk ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[https://www.uniprot.org/uniprot/HEXNO_RALSU HEXNO_RALSU]] Catalyzes the oxidation of a range of monosaccharides in vitro, displaying the highest activity with N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc), with a reduction of O2 to H2O2. Acts upon the C1 carbon of the GlcNAc or GalNAc molecule, producing the corresponding lactone, which can spontaneously hydrolyze. Its biological function is unclear, but its main function might be connected to extracellular production of hydrogen peroxide to compete with other organisms through oxidative stress, or support the action of peroxidases and peroxygenases.<ref>PMID:34709726</ref> | + | [[https://www.uniprot.org/uniprot/HEXNO_RALSU HEXNO_RALSU]] Catalyzes the oxidation of a range of monosaccharides in vitro, displaying the highest activity with N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc), with a reduction of O2 to H2O2. Acts upon the C1 carbon of the GlcNAc or GalNAc molecule, producing the corresponding lactone, which can spontaneously hydrolyze. Its biological function is unclear, but its main function might be connected to extracellular production of hydrogen peroxide to compete with other organisms through oxidative stress, or support the action of peroxidases and peroxygenases.<ref>PMID:34709726</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Ralstonia solanacearum]] |
| - | [[Category: Boverio | + | [[Category: Boverio A]] |
| - | [[Category: Fraaije | + | [[Category: Fraaije MW]] |
| - | [[Category: Rozeboom | + | [[Category: Rozeboom HJ]] |
| - | + | ||
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Revision as of 03:25, 8 September 2022
Structure of the N-acetyl-D-glucosamine oxidase from Ralstonia Solanacearum
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