7p71

==The PDZ domain of MAGI1_2 complexed with the PDZ-binding motif of HPV35-E6==

<StructureSection load='7p71' size='340' side='right'caption='[[7p71]], [[Resolution|resolution]] 2.60&Aring;' scene=''>

<table><tr><td colspan='2'>[[7p71]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_papillomavirus_35 Human papillomavirus 35]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P71 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p71 OCA], [https://pdbe.org/7p71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p71 RCSB], [https://www.ebi.ac.uk/pdbsum/7p71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p71 ProSAT]</span></td></tr>

== Function ==

[[https://www.uniprot.org/uniprot/MAGI1_HUMAN MAGI1_HUMAN]] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).[[https://www.uniprot.org/uniprot/ANXA2_HUMAN ANXA2_HUMAN]] Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.

[[Category: Homo sapiens]]

[[Category: Human papillomavirus 35]]

[[Category: Cousido-Siah A]]

[[Category: Trave G]]