7rj4

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<StructureSection load='7rj4' size='340' side='right'caption='[[7rj4]], [[Resolution|resolution]] 3.32&Aring;' scene=''>
<StructureSection load='7rj4' size='340' side='right'caption='[[7rj4]], [[Resolution|resolution]] 3.32&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7rj4]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RJ4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7rj4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RJ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RJ4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=QNG:N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide'>QNG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=QNG:N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide'>QNG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7rar|7rar]], [[7rao|7rao]], [[7rhn|7rhn]], [[7rhm|7rhm]], [[7rj2|7rj2]]</div></td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rj4 OCA], [https://pdbe.org/7rj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rj4 RCSB], [https://www.ebi.ac.uk/pdbsum/7rj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rj4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rj4 OCA], [https://pdbe.org/7rj4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rj4 RCSB], [https://www.ebi.ac.uk/pdbsum/7rj4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rj4 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/B6DRA0_9HIV1 B6DRA0_9HIV1]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bester, S M]]
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[[Category: Bester SM]]
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[[Category: Kvaratskhelia, M]]
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[[Category: Kvaratskhelia M]]
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[[Category: Inhibitor]]
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[[Category: Viral protein]]
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[[Category: Viral protein-inhibitor complex]]
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Revision as of 04:13, 8 September 2022

Co-crystal structure of lenacapavir bound to N74D mutant of disulfide stabilized HIV-1 CA hexamer

PDB ID 7rj4

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