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7rj9

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==Crystal structure of the Vitronectin hemopexin-like domain binding Calcium==
==Crystal structure of the Vitronectin hemopexin-like domain binding Calcium==
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<StructureSection load='7rj9' size='340' side='right'caption='[[7rj9]]' scene=''>
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<StructureSection load='7rj9' size='340' side='right'caption='[[7rj9]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RJ9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7rj9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RJ9 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rj9 OCA], [https://pdbe.org/7rj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rj9 RCSB], [https://www.ebi.ac.uk/pdbsum/7rj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rj9 ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rj9 OCA], [https://pdbe.org/7rj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rj9 RCSB], [https://www.ebi.ac.uk/pdbsum/7rj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rj9 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/VTNC_HUMAN VTNC_HUMAN]] Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Aleshin AE]]
[[Category: Aleshin AE]]
[[Category: Marassi FM]]
[[Category: Marassi FM]]

Revision as of 04:13, 8 September 2022

Crystal structure of the Vitronectin hemopexin-like domain binding Calcium

PDB ID 7rj9

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