7z8k
From Proteopedia
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| - | ==== | + | ==Cytoplasmic dynein (A1) bound to BICDR1== |
| - | <StructureSection load='7z8k' size='340' side='right'caption='[[7z8k]]' scene=''> | + | <StructureSection load='7z8k' size='340' side='right'caption='[[7z8k]], [[Resolution|resolution]] 4.37Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7z8k]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z8K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z8K FirstGlance]. <br> |
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z8k OCA], [https://pdbe.org/7z8k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z8k RCSB], [https://www.ebi.ac.uk/pdbsum/7z8k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z8k ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z8k OCA], [https://pdbe.org/7z8k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z8k RCSB], [https://www.ebi.ac.uk/pdbsum/7z8k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z8k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [[https://www.uniprot.org/uniprot/DYHC1_HUMAN DYHC1_HUMAN]] Autosomal dominant childhood-onset proximal spinal muscular atrophy without contractures;Autosomal dominant non-syndromic intellectual disability;Autosomal dominant Charcot-Marie-Tooth disease type 2O. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DYHC1_HUMAN DYHC1_HUMAN]] Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Plays a role in mitotic spindle assembly and metaphase plate congression (PubMed:27462074).<ref>PMID:27462074</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Actin-related protein 3D structures|Actin-related protein 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| + | [[Category: Sus scrofa]] | ||
| + | [[Category: Carter AP]] | ||
| + | [[Category: Chaaban S]] | ||
Revision as of 04:19, 8 September 2022
Cytoplasmic dynein (A1) bound to BICDR1
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