7p2x

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==E.coli GyrB24 with inhibitor KOB20 (EBL2583)==
==E.coli GyrB24 with inhibitor KOB20 (EBL2583)==
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<StructureSection load='7p2x' size='340' side='right'caption='[[7p2x]]' scene=''>
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<StructureSection load='7p2x' size='340' side='right'caption='[[7p2x]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2X FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7p2x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2X FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2x OCA], [https://pdbe.org/7p2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2x RCSB], [https://www.ebi.ac.uk/pdbsum/7p2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2x ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4Q6:(2Z)-2-[[4,5-bis(bromanyl)-1H-pyrrol-2-yl]carbonylimino]-3-(phenylmethyl)-1,3-benzothiazole-6-carboxylic+acid'>4Q6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2x OCA], [https://pdbe.org/7p2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2x RCSB], [https://www.ebi.ac.uk/pdbsum/7p2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2x ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/GYRB_ECOLI GYRB_ECOLI]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.<ref>PMID:12051843</ref> <ref>PMID:18642932</ref> <ref>PMID:20675723</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Benek O]]
[[Category: Benek O]]

Revision as of 04:55, 8 September 2022

E.coli GyrB24 with inhibitor KOB20 (EBL2583)

PDB ID 7p2x

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