7p33
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide== |
| - | <StructureSection load='7p33' size='340' side='right'caption='[[7p33]]' scene=''> | + | <StructureSection load='7p33' size='340' side='right'caption='[[7p33]], [[Resolution|resolution]] 2.79Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7p33]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_herpesvirus_4_strain_B95-8 Human herpesvirus 4 strain B95-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P33 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P33 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p33 OCA], [https://pdbe.org/7p33 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p33 RCSB], [https://www.ebi.ac.uk/pdbsum/7p33 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p33 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p33 OCA], [https://pdbe.org/7p33 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p33 RCSB], [https://www.ebi.ac.uk/pdbsum/7p33 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p33 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/EAR_EBVB9 EAR_EBVB9]] Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic proteins to prevent mitochondria permeabilization, release of cytochrome c and subsequent apoptosis of the host cell. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Human herpesvirus 4 strain B95-8]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Hinds MG]] |
| + | [[Category: Kvansakul M]] | ||
| + | [[Category: Suraweera CD]] | ||
Revision as of 04:55, 8 September 2022
Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide
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