6o6e
From Proteopedia
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<StructureSection load='6o6e' size='340' side='right'caption='[[6o6e]], [[Resolution|resolution]] 2.14Å' scene=''> | <StructureSection load='6o6e' size='340' side='right'caption='[[6o6e]], [[Resolution|resolution]] 2.14Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6o6e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[6o6e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_protegens_Pf-5 Pseudomonas protegens Pf-5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6O6E FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=I5M:5-deoxy-5-({(2S)-2-({2-[(N-{(2R)-4-[(dioxo-lambda~5~-phosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-beta-alanyl)amino]ethyl}sulfanyl)-2-[(2S)-pyrrolidin-2-yl]ethanesulfonyl}amino)adenosine'>I5M</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=I5M:5-deoxy-5-({(2S)-2-({2-[(N-{(2R)-4-[(dioxo-lambda~5~-phosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-beta-alanyl)amino]ethyl}sulfanyl)-2-[(2S)-pyrrolidin-2-yl]ethanesulfonyl}amino)adenosine'>I5M</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pltF, PFL_2792 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=220664 PSEF5]), pltL, PFL_2786 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=220664 PSEF5])</td></tr> | ||
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-proline--[L-prolyl-carrier_protein]_ligase L-proline--[L-prolyl-carrier protein] ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.2.1.53 6.2.1.53] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o6e OCA], [https://pdbe.org/6o6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o6e RCSB], [https://www.ebi.ac.uk/pdbsum/6o6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o6e ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o6e OCA], [https://pdbe.org/6o6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o6e RCSB], [https://www.ebi.ac.uk/pdbsum/6o6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o6e ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[https://www.uniprot.org/uniprot/PLTF_PSEF5 PLTF_PSEF5]] Involved in the biosynthesis of pyoluteorin. Catalyzes the conversion of L-proline to L-prolyl-AMP and the transfer of the L-prolyl group to acyl carrier protein PltL.<ref>PMID:11880032</ref> | + | [[https://www.uniprot.org/uniprot/PLTF_PSEF5 PLTF_PSEF5]] Involved in the biosynthesis of pyoluteorin. Catalyzes the conversion of L-proline to L-prolyl-AMP and the transfer of the L-prolyl group to acyl carrier protein PltL.<ref>PMID:11880032</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Pseudomonas protegens Pf-5]] |
| - | [[Category: Corpuz | + | [[Category: Corpuz JC]] |
| - | [[Category: Podust | + | [[Category: Podust LM]] |
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Revision as of 05:19, 8 September 2022
Crystal structure of PltF trapped with PltL using a proline adenosine vinylsulfonamide inhibitor
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