7t0z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
====
+
==Complex of GABA-A synaptic receptor with autoimmune antibody Fab175==
-
<StructureSection load='7t0z' size='340' side='right'caption='[[7t0z]]' scene=''>
+
<StructureSection load='7t0z' size='340' side='right'caption='[[7t0z]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7t0z]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T0Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T0Z FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t0z OCA], [https://pdbe.org/7t0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t0z RCSB], [https://www.ebi.ac.uk/pdbsum/7t0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t0z ProSAT]</span></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABU:GAMMA-AMINO-BUTANOIC+ACID'>ABU</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t0z OCA], [https://pdbe.org/7t0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t0z RCSB], [https://www.ebi.ac.uk/pdbsum/7t0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t0z ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[[https://www.uniprot.org/uniprot/GBRB2_HUMAN GBRB2_HUMAN]] Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.<ref>PMID:19763268</ref> <ref>PMID:8264558</ref>
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Z-disk]]
+
[[Category: Hibbs RE]]
 +
[[Category: Kreye J]]
 +
[[Category: Noviello CM]]
 +
[[Category: Pruss H]]
 +
[[Category: Teng J]]

Revision as of 05:28, 8 September 2022

Complex of GABA-A synaptic receptor with autoimmune antibody Fab175

PDB ID 7t0z

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools