7t0z
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Complex of GABA-A synaptic receptor with autoimmune antibody Fab175== |
| - | <StructureSection load='7t0z' size='340' side='right'caption='[[7t0z]]' scene=''> | + | <StructureSection load='7t0z' size='340' side='right'caption='[[7t0z]], [[Resolution|resolution]] 3.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7t0z]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T0Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T0Z FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t0z OCA], [https://pdbe.org/7t0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t0z RCSB], [https://www.ebi.ac.uk/pdbsum/7t0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t0z ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABU:GAMMA-AMINO-BUTANOIC+ACID'>ABU</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t0z OCA], [https://pdbe.org/7t0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t0z RCSB], [https://www.ebi.ac.uk/pdbsum/7t0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t0z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/GBRB2_HUMAN GBRB2_HUMAN]] Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.<ref>PMID:19763268</ref> <ref>PMID:8264558</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Hibbs RE]] |
| + | [[Category: Kreye J]] | ||
| + | [[Category: Noviello CM]] | ||
| + | [[Category: Pruss H]] | ||
| + | [[Category: Teng J]] | ||
Revision as of 05:28, 8 September 2022
Complex of GABA-A synaptic receptor with autoimmune antibody Fab175
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Categories: Homo sapiens | Large Structures | Hibbs RE | Kreye J | Noviello CM | Pruss H | Teng J
