7w48

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====
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==Crystal structure of the gastric proton pump complexed with PF-03716556==
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<StructureSection load='7w48' size='340' side='right'caption='[[7w48]]' scene=''>
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<StructureSection load='7w48' size='340' side='right'caption='[[7w48]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7w48]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W48 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w48 OCA], [https://pdbe.org/7w48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w48 RCSB], [https://www.ebi.ac.uk/pdbsum/7w48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w48 ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8BZ:N-(2-hydroxyethyl)-N,2-dimethyl-8-[[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino]imidazo[1,2-a]pyridine-6-carboxamide'>8BZ</scene>, <scene name='pdbligand=BFD:ASPARTATE+BERYLLIUM+TRIFLUORIDE'>BFD</scene>, <scene name='pdbligand=CE1:O-DODECANYL+OCTAETHYLENE+GLYCOL'>CE1</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene>, <scene name='pdbligand=RB:RUBIDIUM+ION'>RB</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w48 OCA], [https://pdbe.org/7w48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w48 RCSB], [https://www.ebi.ac.uk/pdbsum/7w48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w48 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG]] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Sus scrofa]]
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[[Category: Abe K]]
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[[Category: Tanaka S]]

Revision as of 05:33, 8 September 2022

Crystal structure of the gastric proton pump complexed with PF-03716556

PDB ID 7w48

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