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7owv
From Proteopedia
(Difference between revisions)
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==Crystal structure of IpgC in complex with a follow-up compound based on J20== | ==Crystal structure of IpgC in complex with a follow-up compound based on J20== | ||
| - | <StructureSection load='7owv' size='340' side='right'caption='[[7owv]]' scene=''> | + | <StructureSection load='7owv' size='340' side='right'caption='[[7owv]], [[Resolution|resolution]] 1.59Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OWV FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7owv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OWV FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7owv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7owv OCA], [https://pdbe.org/7owv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7owv RCSB], [https://www.ebi.ac.uk/pdbsum/7owv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7owv ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2IY:3-(4-chlorophenyl)-5-methylsulfanyl-1~{H}-pyrazole-4-carbonitrile'>2IY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7owv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7owv OCA], [https://pdbe.org/7owv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7owv RCSB], [https://www.ebi.ac.uk/pdbsum/7owv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7owv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL]] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Shigella flexneri]] | ||
[[Category: Gardonyi M]] | [[Category: Gardonyi M]] | ||
[[Category: Heine A]] | [[Category: Heine A]] | ||
[[Category: Klebe G]] | [[Category: Klebe G]] | ||
Revision as of 05:41, 8 September 2022
Crystal structure of IpgC in complex with a follow-up compound based on J20
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