7owz
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine and in the presence of Anderson-Evans type (TEW) and Strandberg type polyoxometalate (POM)== |
| - | <StructureSection load='7owz' size='340' side='right'caption='[[7owz]]' scene=''> | + | <StructureSection load='7owz' size='340' side='right'caption='[[7owz]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7owz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OWZ FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7owz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7owz OCA], [https://pdbe.org/7owz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7owz RCSB], [https://www.ebi.ac.uk/pdbsum/7owz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7owz ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2I2:pentadecaoxodiphosphopentatungstate'>2I2</scene>, <scene name='pdbligand=QEI:2-AMINO-5-({[(1S,4S,5R)-4,5-DIHYDROXYCYCLOPENT-2-EN-1-YL]AMINO}METHYL)-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE'>QEI</scene>, <scene name='pdbligand=TEW:6-TUNGSTOTELLURATE(VI)'>TEW</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7owz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7owz OCA], [https://pdbe.org/7owz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7owz RCSB], [https://www.ebi.ac.uk/pdbsum/7owz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7owz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/QTRT2_MOUSE QTRT2_MOUSE]] Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_03043]<ref>PMID:19414587</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| + | [[Category: Heine A]] | ||
| + | [[Category: Reuter K]] | ||
| + | [[Category: Sebastiani M]] | ||
Revision as of 05:41, 8 September 2022
Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine and in the presence of Anderson-Evans type (TEW) and Strandberg type polyoxometalate (POM)
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