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7syt

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====
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==Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt)==
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<StructureSection load='7syt' size='340' side='right'caption='[[7syt]]' scene=''>
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<StructureSection load='7syt' size='340' side='right'caption='[[7syt]], [[Resolution|resolution]] 4.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7syt]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SYT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SYT FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7syt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7syt OCA], [https://pdbe.org/7syt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7syt RCSB], [https://www.ebi.ac.uk/pdbsum/7syt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7syt ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7syt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7syt OCA], [https://pdbe.org/7syt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7syt RCSB], [https://www.ebi.ac.uk/pdbsum/7syt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7syt ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/G1TLT8_RABIT G1TLT8_RABIT]] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.[HAMAP-Rule:MF_03016]
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__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Oryctolagus cuniculus]]
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[[Category: Abaeva IS]]
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[[Category: Brown ZP]]
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[[Category: De S]]
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[[Category: Frank J]]
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[[Category: Hellen CUT]]
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[[Category: Pestova TV]]

Revision as of 05:50, 8 September 2022

Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt)

PDB ID 7syt

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