7xbw

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====
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==Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with Gi1==
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<StructureSection load='7xbw' size='340' side='right'caption='[[7xbw]]' scene=''>
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<StructureSection load='7xbw' size='340' side='right'caption='[[7xbw]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7xbw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XBW FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xbw OCA], [https://pdbe.org/7xbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xbw RCSB], [https://www.ebi.ac.uk/pdbsum/7xbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xbw ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xbw OCA], [https://pdbe.org/7xbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xbw RCSB], [https://www.ebi.ac.uk/pdbsum/7xbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xbw ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Han S]]
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[[Category: Lu M]]
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[[Category: Wu B]]
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[[Category: Zhao Q]]
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[[Category: Zhao W]]
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[[Category: Zhu Y]]

Revision as of 05:55, 8 September 2022

Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with Gi1

PDB ID 7xbw

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