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8d1e
From Proteopedia
(Difference between revisions)
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==hBest2 1uM Ca2+ (Ca2+-bound) closed state== | ==hBest2 1uM Ca2+ (Ca2+-bound) closed state== | ||
| - | <StructureSection load='8d1e' size='340' side='right'caption='[[8d1e]]' scene=''> | + | <StructureSection load='8d1e' size='340' side='right'caption='[[8d1e]], [[Resolution|resolution]] 1.78Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D1E FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[8d1e]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D1E FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d1e OCA], [https://pdbe.org/8d1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d1e RCSB], [https://www.ebi.ac.uk/pdbsum/8d1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d1e ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DU0:2-[2-[(1~{S},2~{S},4~{S},5~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2-oxane]-16-yl]oxyethyl]propane-1,3-diol'>DU0</scene>, <scene name='pdbligand=MC3:1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE'>MC3</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d1e OCA], [https://pdbe.org/8d1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d1e RCSB], [https://www.ebi.ac.uk/pdbsum/8d1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d1e ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/BEST2_HUMAN BEST2_HUMAN]] Forms calcium-sensitive chloride channels. Permeable to bicarbonate.<ref>PMID:11904445</ref> <ref>PMID:12907679</ref> <ref>PMID:18400985</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Bestrophin 3D structures|Bestrophin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Hendrickson WA]] | [[Category: Hendrickson WA]] | ||
Revision as of 05:58, 8 September 2022
hBest2 1uM Ca2+ (Ca2+-bound) closed state
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