7m45
From Proteopedia
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| - | ==== | + | ==DNA Polymerase Lambda, TTP:At Mg2+ Reaction State Ternary Complex, 120 sec== |
| - | <StructureSection load='7m45' size='340' side='right'caption='[[7m45]]' scene=''> | + | <StructureSection load='7m45' size='340' side='right'caption='[[7m45]], [[Resolution|resolution]] 1.89Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7m45]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M45 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m45 OCA], [https://pdbe.org/7m45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m45 RCSB], [https://www.ebi.ac.uk/pdbsum/7m45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m45 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene>, <scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m45 OCA], [https://pdbe.org/7m45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m45 RCSB], [https://www.ebi.ac.uk/pdbsum/7m45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m45 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN]] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Synthetic construct]] |
| + | [[Category: Jamsen JA]] | ||
| + | [[Category: Wilson SH]] | ||
Revision as of 06:38, 8 September 2022
DNA Polymerase Lambda, TTP:At Mg2+ Reaction State Ternary Complex, 120 sec
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