7m4g

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====
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==DNA Polymerase Lambda, dCTP:At Mg2+ Product State Ternary Complex, 960 min==
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<StructureSection load='7m4g' size='340' side='right'caption='[[7m4g]]' scene=''>
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<StructureSection load='7m4g' size='340' side='right'caption='[[7m4g]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7m4g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7M4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7M4G FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m4g OCA], [https://pdbe.org/7m4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m4g RCSB], [https://www.ebi.ac.uk/pdbsum/7m4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m4g ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7m4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7m4g OCA], [https://pdbe.org/7m4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7m4g RCSB], [https://www.ebi.ac.uk/pdbsum/7m4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7m4g ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN]] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Jamsen JA]]
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[[Category: Wilson SH]]

Revision as of 06:39, 8 September 2022

DNA Polymerase Lambda, dCTP:At Mg2+ Product State Ternary Complex, 960 min

PDB ID 7m4g

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