7mqm
From Proteopedia
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<StructureSection load='7mqm' size='340' side='right'caption='[[7mqm]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='7mqm' size='340' side='right'caption='[[7mqm]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[7mqm]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MQM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MQM FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7mqm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MQM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MQM FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=51G:GENTAMICIN+C1'>51G</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=51G:GENTAMICIN+C1'>51G</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mqm OCA], [https://pdbe.org/7mqm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mqm RCSB], [https://www.ebi.ac.uk/pdbsum/7mqm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mqm ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mqm OCA], [https://pdbe.org/7mqm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mqm RCSB], [https://www.ebi.ac.uk/pdbsum/7mqm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mqm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[https://www.uniprot.org/uniprot/AACC3_PSEAI AACC3_PSEAI]] Resistance to antibiotics containing the 2-deoxy-streptamine ring including dibekacin, gentamicin, kanamycin, sisomicin, tobramycin, neomycin and to a lesser extent netilmicin. | + | [[https://www.uniprot.org/uniprot/AACC3_PSEAI AACC3_PSEAI]] Resistance to antibiotics containing the 2-deoxy-streptamine ring including dibekacin, gentamicin, kanamycin, sisomicin, tobramycin, neomycin and to a lesser extent netilmicin. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Pseudomonas aeruginosa]] |
| - | [[Category: | + | [[Category: Berghuis AM]] |
| - | [[Category: | + | [[Category: Zielinski M]] |
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Revision as of 06:39, 8 September 2022
AAC(3)-IIIa in complex with CoA and gentamicin
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