7sqo
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Structure of the orexin-2 receptor(OX2R) bound to TAK-925, Gi and scFv16== |
| - | <StructureSection load='7sqo' size='340' side='right'caption='[[7sqo]]' scene=''> | + | <StructureSection load='7sqo' size='340' side='right'caption='[[7sqo]], [[Resolution|resolution]] 3.17Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7sqo]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SQO FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sqo OCA], [https://pdbe.org/7sqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sqo RCSB], [https://www.ebi.ac.uk/pdbsum/7sqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sqo ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A6F:methyl+(2R,3S)-3-[(methanesulfonyl)amino]-2-({[(1s,4S)-4-phenylcyclohexyl]oxy}methyl)piperidine-1-carboxylate'>A6F</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sqo OCA], [https://pdbe.org/7sqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sqo RCSB], [https://www.ebi.ac.uk/pdbsum/7sqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sqo ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/OX2R_HUMAN OX2R_HUMAN]] Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Synthetic construct]] |
| + | [[Category: Flinspach M]] | ||
| + | [[Category: Kang Y]] | ||
| + | [[Category: McGrath AP]] | ||
Revision as of 07:22, 8 September 2022
Structure of the orexin-2 receptor(OX2R) bound to TAK-925, Gi and scFv16
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