7u5o

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==CRYSTAL STRUCTURE OF THE BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE 2 LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-B==
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<StructureSection load='7u5o' size='340' side='right'caption='[[7u5o]]' scene=''>
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<StructureSection load='7u5o' size='340' side='right'caption='[[7u5o]], [[Resolution|resolution]] 3.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7u5o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7U5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7U5O FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u5o OCA], [https://pdbe.org/7u5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u5o RCSB], [https://www.ebi.ac.uk/pdbsum/7u5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u5o ProSAT]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u5o OCA], [https://pdbe.org/7u5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u5o RCSB], [https://www.ebi.ac.uk/pdbsum/7u5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u5o ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/INHBB_HUMAN INHBB_HUMAN]] Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Chu KY]]
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[[Category: Malik A]]
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[[Category: Martinez-Hackert E]]
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[[Category: Thamilselvan V]]

Revision as of 07:22, 8 September 2022

CRYSTAL STRUCTURE OF THE BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE 2 LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-B

PDB ID 7u5o

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