4dfu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin==
==Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin==
-
<StructureSection load='4dfu' size='340' side='right' caption='[[4dfu]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
+
<StructureSection load='4dfu' size='340' side='right'caption='[[4dfu]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4dfu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptococcus_casseliflavus"_vaughan_et_al._1979 "streptococcus casseliflavus" vaughan et al. 1979]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3vcq 3vcq] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3r82 3r82]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DFU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DFU FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4dfu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_casseliflavus Enterococcus casseliflavus]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3vcq 3vcq] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3r82 3r82]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DFU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DFU FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=QUE:3,5,7,3,4-PENTAHYDROXYFLAVONE'>QUE</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=QUE:3,5,7,3,4-PENTAHYDROXYFLAVONE'>QUE</scene></td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dfu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dfu OCA], [https://pdbe.org/4dfu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dfu RCSB], [https://www.ebi.ac.uk/pdbsum/4dfu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dfu ProSAT]</span></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dbx|4dbx]], [[4de4|4de4]], [[4dfb|4dfb]]</td></tr>
+
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APH(2")-Id ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=37734 "Streptococcus casseliflavus" Vaughan et al. 1979])</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dfu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dfu OCA], [http://pdbe.org/4dfu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dfu RCSB], [http://www.ebi.ac.uk/pdbsum/4dfu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dfu ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[[https://www.uniprot.org/uniprot/O68183_ENTCA O68183_ENTCA]]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 20:
==See Also==
==See Also==
-
*[[Phosphotransferase|Phosphotransferase]]
+
*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Streptococcus casseliflavus vaughan et al. 1979]]
+
[[Category: Enterococcus casseliflavus]]
-
[[Category: Anderson, W F]]
+
[[Category: Large Structures]]
-
[[Category: Structural genomic]]
+
[[Category: Anderson WF]]
-
[[Category: Dong, A]]
+
[[Category: Di Leo R]]
-
[[Category: Egorova, E]]
+
[[Category: Dong A]]
-
[[Category: Evdokimova, E]]
+
[[Category: Egorova E]]
-
[[Category: Leo, R Di]]
+
[[Category: Evdokimova E]]
-
[[Category: Li, H]]
+
[[Category: Li H]]
-
[[Category: Minasov, G]]
+
[[Category: Minasov G]]
-
[[Category: Savchenko, A]]
+
[[Category: Savchenko A]]
-
[[Category: Shakya, T]]
+
[[Category: Shakya T]]
-
[[Category: Stogios, P J]]
+
[[Category: Stogios PJ]]
-
[[Category: Wright, G D]]
+
[[Category: Wright GD]]
-
[[Category: Aminoglycoside phosphotransferase]]
+
-
[[Category: Aminoglycoside]]
+
-
[[Category: Antibotic]]
+
-
[[Category: Csgid]]
+
-
[[Category: Eukaryotic protein kinase-like fold]]
+
-
[[Category: Flavanoid]]
+
-
[[Category: Intracellular]]
+
-
[[Category: Kanamycin]]
+
-
[[Category: Kinase]]
+
-
[[Category: Quercetin]]
+
-
[[Category: Transferase]]
+
-
[[Category: Transferase-antibiotic-inhibitor complex]]
+
-
[[Category: Transferase-antibotic-inhibitor complex]]
+

Revision as of 08:16, 21 September 2022

Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin

PDB ID 4dfu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4dfu"
Personal tools