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4dkk

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==The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer==
==The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer==
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<StructureSection load='4dkk' size='340' side='right' caption='[[4dkk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='4dkk' size='340' side='right'caption='[[4dkk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4dkk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DKK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4dkk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DKK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STAU, STAU1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkk OCA], [https://pdbe.org/4dkk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dkk RCSB], [https://www.ebi.ac.uk/pdbsum/4dkk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dkk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkk OCA], [http://pdbe.org/4dkk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dkk RCSB], [http://www.ebi.ac.uk/pdbsum/4dkk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dkk ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/STAU1_HUMAN STAU1_HUMAN]] Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
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[[https://www.uniprot.org/uniprot/STAU1_HUMAN STAU1_HUMAN]] Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Gleghorn, M L]]
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[[Category: Large Structures]]
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[[Category: Beta sheet]]
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[[Category: Gleghorn ML]]
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[[Category: Dimerization]]
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[[Category: Protein binding]]
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[[Category: Rbd]]
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[[Category: Rna binding protein]]
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[[Category: Swapping-motif]]
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Revision as of 08:23, 21 September 2022

The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer

PDB ID 4dkk

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