User:Ann Taylor/Sandbox 1
From Proteopedia
(Difference between revisions)
| Line 16: | Line 16: | ||
The protein binds as a <scene name='92/925538/Dimer/2'>dimer</scene> to a symmetrical 17-base-pair sequence. | The protein binds as a <scene name='92/925538/Dimer/2'>dimer</scene> to a symmetrical 17-base-pair sequence. | ||
| + | <scene name='92/927197/Dimer/2'>Dimer</scene> | ||
==Domains== | ==Domains== | ||
| Line 25: | Line 26: | ||
Each subunit fold into three distinct modules: a compact, <scene name='92/925552/Metal_binding_domain/1'>metal binding domain</scene> (residues 8-40), an <scene name='92/925552/Extended_linker/1'>extended linker</scene> (41-49), and an <scene name='92/925552/Alpha-helical_dimerization/1'>alpha-helical dimerization</scene> element (50-64). | Each subunit fold into three distinct modules: a compact, <scene name='92/925552/Metal_binding_domain/1'>metal binding domain</scene> (residues 8-40), an <scene name='92/925552/Extended_linker/1'>extended linker</scene> (41-49), and an <scene name='92/925552/Alpha-helical_dimerization/1'>alpha-helical dimerization</scene> element (50-64). | ||
| + | |||
| + | <scene name='92/927197/Dimer/3'>Text To Be Displayed</scene> | ||
==Metal binding== | ==Metal binding== | ||
| + | |||
A small, Zn(2+)-containing domain recognizes a conserved CCG triplet at each end of the site through direct contacts with the major groove. The metal binding domain contains <scene name='92/925538/Cysteine_metal_binding/3'>cysteine residues</scene> that coordinate to the metal as shown as cadmium. | A small, Zn(2+)-containing domain recognizes a conserved CCG triplet at each end of the site through direct contacts with the major groove. The metal binding domain contains <scene name='92/925538/Cysteine_metal_binding/3'>cysteine residues</scene> that coordinate to the metal as shown as cadmium. | ||
The cadmium is coordinated to this domain via interactions with several <scene name='92/925552/Cysteine_coordination_sites/1'>cysteine residues</scene>. | The cadmium is coordinated to this domain via interactions with several <scene name='92/925552/Cysteine_coordination_sites/1'>cysteine residues</scene>. | ||
| + | |||
| + | <scene name='92/927197/Dimer/1'>Text To Be Displayed</scene> | ||
The Metal Binding Domain binds the metal through the use of <scene name='92/925551/Dimer_practice/13'>cysteine residues</scene>. | The Metal Binding Domain binds the metal through the use of <scene name='92/925551/Dimer_practice/13'>cysteine residues</scene>. | ||
Revision as of 03:12, 22 September 2022
| |||||||||||
