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1iiu

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[[Image:1iiu.jpg|left|200px]]
[[Image:1iiu.jpg|left|200px]]
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{{Structure
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|PDB= 1iiu |SIZE=350|CAPTION= <scene name='initialview01'>1iiu</scene>, resolution 2.50&Aring;
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The line below this paragraph, containing "STRUCTURE_1iiu", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=RTL:RETINOL'>RTL</scene>
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{{STRUCTURE_1iiu| PDB=1iiu | SCENE= }}
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|RELATEDENTRY=[[1aqb|1AQB]], [[1hbp|1HBP]], [[1hbq|1HBQ]], [[1rbp|1RBP]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iiu OCA], [http://www.ebi.ac.uk/pdbsum/1iiu PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1iiu RCSB]</span>
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'''Chicken plasma retinol-binding protein (RBP)'''
'''Chicken plasma retinol-binding protein (RBP)'''
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[[Category: Calderone, V.]]
[[Category: Calderone, V.]]
[[Category: Zanotti, G.]]
[[Category: Zanotti, G.]]
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[[Category: rbp]]
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[[Category: Rbp]]
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[[Category: retinol]]
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[[Category: Retinol]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:03:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:20:28 2008''
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Revision as of 17:03, 2 May 2008

Image:1iiu.jpg

Template:STRUCTURE 1iiu

Chicken plasma retinol-binding protein (RBP)


Overview

The crystal structure of the specific carrier of retinol (retinol-binding protein, RBP) purified from chicken plasma has been determined (space group P2(1)2(1)2(1), with a=46.06(5) A, b=53.56(6) A, c=73.41(8) A, and one protein molecule in the asymmetric unit). Despite being obtained from a species phylogenetically distant from mammals, chicken holoRBP has an overall structure that closely resembles the previously determined structures of mammalian holoRBPs. The lack in chicken RBP of eight carboxy-terminal amino acid residues characteristic of mammalian RBPs does not significantly affect the protein structure. A distinctive feature of the avian protein is a better definition of the loop 63-67, close to the opening of the beta-barrel cavity accommodating the retinol molecule, which is rather disordered in the structures of mammalian RBPs.

About this Structure

1IIU is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Structure of chicken plasma retinol-binding protein., Zanotti G, Calderone V, Beda M, Malpeli G, Folli C, Berni R, Biochim Biophys Acta. 2001 Nov 26;1550(1):64-9. PMID:11738088 Page seeded by OCA on Fri May 2 20:03:05 2008

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