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7vie
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with S1P== | |
| - | + | <StructureSection load='7vie' size='340' side='right'caption='[[7vie]], [[Resolution|resolution]] 2.86Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7vie]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VIE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=S1P:(2S,3R,4E)-2-AMINO-3-HYDROXYOCTADEC-4-EN-1-YL+DIHYDROGEN+PHOSPHATE'>S1P</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vie OCA], [https://pdbe.org/7vie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vie RCSB], [https://www.ebi.ac.uk/pdbsum/7vie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vie ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Gan B]] | ||
| + | [[Category: Ren RB]] | ||
| + | [[Category: Xiao QJ]] | ||
| + | [[Category: Yu LY]] | ||
Revision as of 06:18, 28 September 2022
Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with S1P
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Categories: Homo sapiens | Large Structures | Mus musculus | Gan B | Ren RB | Xiao QJ | Yu LY
