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4e8y

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==Crystal Structure of Burkholderia cenocepacia HldA in Complex with an ATP-competitive Inhibitor==
==Crystal Structure of Burkholderia cenocepacia HldA in Complex with an ATP-competitive Inhibitor==
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<StructureSection load='4e8y' size='340' side='right' caption='[[4e8y]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='4e8y' size='340' side='right'caption='[[4e8y]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4e8y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burcj Burcj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E8Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E8Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4e8y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cenocepacia_J2315 Burkholderia cenocepacia J2315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E8Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E8Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IHA:{[2-({[5-(2,6-DIMETHOXYPHENYL)-1,2,4-TRIAZIN-3-YL]AMINO}METHYL)-1,3-BENZOTHIAZOL-5-YL]OXY}ACETIC+ACID'>IHA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=M7B:7-O-PHOSPHONO-D-GLYCERO-BETA-D-MANNO-HEPTOPYRANOSE'>M7B</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IHA:{[2-({[5-(2,6-DIMETHOXYPHENYL)-1,2,4-TRIAZIN-3-YL]AMINO}METHYL)-1,3-BENZOTHIAZOL-5-YL]OXY}ACETIC+ACID'>IHA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=M7B:7-O-PHOSPHONO-D-GLYCERO-BETA-D-MANNO-HEPTOPYRANOSE'>M7B</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e84|4e84]], [[4e8w|4e8w]], [[4e8z|4e8z]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e8y OCA], [https://pdbe.org/4e8y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e8y RCSB], [https://www.ebi.ac.uk/pdbsum/4e8y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e8y ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hldA, BceJ2315_28810, BCAL2945 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216591 BURCJ])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e8y OCA], [http://pdbe.org/4e8y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e8y RCSB], [http://www.ebi.ac.uk/pdbsum/4e8y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e8y ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/B4EB35_BURCJ B4EB35_BURCJ]]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Burcj]]
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[[Category: Burkholderia cenocepacia J2315]]
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[[Category: Junop, M S]]
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[[Category: Large Structures]]
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[[Category: Lee, T W]]
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[[Category: Junop MS]]
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[[Category: Verhey, T B]]
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[[Category: Lee T-W]]
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[[Category: Beta-clasp dimerization region]]
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[[Category: Verhey TB]]
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[[Category: Lps-heptose biosynthesis]]
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[[Category: Pfkb carbohydrate kinase]]
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[[Category: Phosphorylation]]
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[[Category: Transferase-transferase inhibitor complex]]
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Revision as of 06:57, 28 September 2022

Crystal Structure of Burkholderia cenocepacia HldA in Complex with an ATP-competitive Inhibitor

PDB ID 4e8y

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