4e9b

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==Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin==
==Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin==
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<StructureSection load='4e9b' size='340' side='right' caption='[[4e9b]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='4e9b' size='340' side='right'caption='[[4e9b]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4e9b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E9B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E9B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4e9b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E9B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e9a|4e9a]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e9b OCA], [https://pdbe.org/4e9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e9b RCSB], [https://www.ebi.ac.uk/pdbsum/4e9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e9b ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">def, def11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 ATCC 43504])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e9b OCA], [http://pdbe.org/4e9b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e9b RCSB], [http://www.ebi.ac.uk/pdbsum/4e9b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e9b ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q672W7_HELPX Q672W7_HELPX]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]
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[[https://www.uniprot.org/uniprot/Q672W7_HELPX Q672W7_HELPX]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43504]]
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[[Category: Helicobacter pylori]]
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[[Category: Peptide deformylase]]
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[[Category: Large Structures]]
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[[Category: Cui, K]]
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[[Category: Cui K]]
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[[Category: Huang, J]]
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[[Category: Huang J]]
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[[Category: Lu, W]]
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[[Category: Lu W]]
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[[Category: Zhu, L]]
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[[Category: Zhu L]]
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[[Category: Hydrolase-hydrolase inhibtior complex]]
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Revision as of 06:58, 28 September 2022

Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin

PDB ID 4e9b

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