4ea2

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==Crystal structure of dehydrosqualene synthase (Crtm) aureus complexed with SQ-109==
==Crystal structure of dehydrosqualene synthase (Crtm) aureus complexed with SQ-109==
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<StructureSection load='4ea2' size='340' side='right' caption='[[4ea2]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='4ea2' size='340' side='right'caption='[[4ea2]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ea2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EA2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EA2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ea2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EA2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene>, <scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene>, <scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e9z|4e9z]], [[4ea0|4ea0]], [[4ea1|4ea1]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ea2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ea2 OCA], [https://pdbe.org/4ea2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ea2 RCSB], [https://www.ebi.ac.uk/pdbsum/4ea2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ea2 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">crtM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4,4'-diapophytoene_synthase 4,4'-diapophytoene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.96 2.5.1.96] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ea2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ea2 OCA], [http://pdbe.org/4ea2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ea2 RCSB], [http://www.ebi.ac.uk/pdbsum/4ea2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ea2 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/CRTM_STAAU CRTM_STAAU]]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4ea2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4ea2" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Squalene synthase|Squalene synthase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 4,4'-diapophytoene synthase]]
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[[Category: Large Structures]]
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[[Category: Li, K]]
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[[Category: Staphylococcus aureus]]
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[[Category: Lin, F Y]]
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[[Category: Li K]]
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[[Category: Liu, Y L]]
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[[Category: Lin F-Y]]
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[[Category: Oldfield, E]]
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[[Category: Liu Y-L]]
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[[Category: Prenyl transferase]]
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[[Category: Oldfield E]]
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[[Category: Transferase-transferase inhibitor complex]]
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Revision as of 06:59, 28 September 2022

Crystal structure of dehydrosqualene synthase (Crtm) aureus complexed with SQ-109

PDB ID 4ea2

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