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4emv

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==Crystal structure of a topoisomerase ATP inhibitor==
==Crystal structure of a topoisomerase ATP inhibitor==
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<StructureSection load='4emv' size='340' side='right' caption='[[4emv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='4emv' size='340' side='right'caption='[[4emv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4emv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_ga47373 Streptococcus pneumoniae ga47373]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EMV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4emv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_GA47373 Streptococcus pneumoniae GA47373]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EMV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0R9:5-{2-(ETHYLCARBAMOYL)-4-[3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1H-PYRROLO[2,3-B]PYRIDIN-5-YL}PYRIDINE-3-CARBOXYLIC+ACID'>0R9</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0R9:5-{2-(ETHYLCARBAMOYL)-4-[3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1H-PYRROLO[2,3-B]PYRIDIN-5-YL}PYRIDINE-3-CARBOXYLIC+ACID'>0R9</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4em7|4em7]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4emv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4emv OCA], [https://pdbe.org/4emv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4emv RCSB], [https://www.ebi.ac.uk/pdbsum/4emv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4emv ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ParE, SPAR94_0831 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=760835 Streptococcus pneumoniae GA47373])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4emv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4emv OCA], [http://pdbe.org/4emv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4emv RCSB], [http://www.ebi.ac.uk/pdbsum/4emv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4emv ProSAT]</span></td></tr>
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</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Topoisomerase|Topoisomerase]]
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*[[Topoisomerase 3D structures|Topoisomerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Streptococcus pneumoniae ga47373]]
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[[Category: Large Structures]]
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[[Category: Boriack-Sjodin, P A]]
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[[Category: Streptococcus pneumoniae GA47373]]
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[[Category: Hull, K]]
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[[Category: Boriack-Sjodin PA]]
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[[Category: Manchester, J]]
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[[Category: Hull K]]
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[[Category: Antimicrobial]]
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[[Category: Manchester J]]
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[[Category: Atp binding]]
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[[Category: Isomerase-isomerase inhibitor complex]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Structure-based drug design]]
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[[Category: Virtual screen]]
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Revision as of 07:18, 28 September 2022

Crystal structure of a topoisomerase ATP inhibitor

PDB ID 4emv

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