1p16

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<StructureSection load='1p16' size='340' side='right'caption='[[1p16]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='1p16' size='340' side='right'caption='[[1p16]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1p16]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_11006_[[monilia_stellatoidea]] Atcc 11006 [[monilia stellatoidea]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P16 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1p16]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P16 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CGT1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5476 ATCC 11006 [[Monilia stellatoidea]]])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/mRNA_guanylyltransferase mRNA guanylyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.50 2.7.7.50] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p16 OCA], [https://pdbe.org/1p16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p16 RCSB], [https://www.ebi.ac.uk/pdbsum/1p16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p16 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p16 OCA], [https://pdbe.org/1p16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p16 RCSB], [https://www.ebi.ac.uk/pdbsum/1p16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p16 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MCE1_CANAX MCE1_CANAX]] Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate (By similarity).
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[https://www.uniprot.org/uniprot/MCE1_CANAX MCE1_CANAX] Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Candida albicans]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: MRNA guanylyltransferase]]
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[[Category: Fabrega C]]
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[[Category: Fabrega, C]]
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[[Category: Lima CD]]
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[[Category: Lima, C D]]
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[[Category: Shen V]]
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[[Category: Shen, V]]
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[[Category: Shuman S]]
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[[Category: Shuman, S]]
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[[Category: Candida albican]]
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[[Category: Capping]]
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[[Category: Ctd]]
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[[Category: Guanylyltransferase]]
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[[Category: Mrna]]
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[[Category: Rna polymerase ii]]
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[[Category: Transcription]]
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[[Category: Transferase]]
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Revision as of 04:28, 30 September 2022

Structure of an mRNA capping enzyme bound to the phosphorylated carboxyl-terminal domain of RNA polymerase II

PDB ID 1p16

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OCA

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